Cheap flights from Southampton to San Francisco

from as little as £838

9 nights in San Francisco, departing Southampton on 21 / May / 2025 with KLM (price found 6 hours ago)

Subject to availability, prices correct of the last 24 hours
San Francisco

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The Southampton / San Francisco route

All 8622 km of it

Cheap flight deals for this route

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San Francisco flight facts

What you need to know

Alternative flights from the UK to San Francisco

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San Francisco

21 / May / 2025 is currently the lowest priced day of the year to fly the Southampton/San Francisco route. There are around 47 flights on any given week from the UK to San Francisco and the cheapest month to fly right now is May.

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Min / Max Temperature (°C)
LOWEST

8 °C

AVG

14 °C

HIGHEST

21 °C

Rainfall (mm)
LOWEST

0 mm

AVG

44.8 mm

HIGHEST

112 mm

Key facts about San Francisco

How to get cheap flights from Southampton to San Francisco

Tips and advice from our flight experts

You’ve searched for flights from Southampton to San Francisco. 47 flights go to or via San Francisco every week, and we've searched them all to make it easy for you to compare your flight options. On average, Virgin Atlantic has the cheapest flights, so look out for them in your search results.

When you fly from Southampton to San Francisco, you'll have four airlines to choose from for your 8622 km journey. If you're planning to fly in peak season, make sure you book in advance to get a reasonable price. Or you could hold on and try to get a last-minute bargain.

If you're fairly flexible about when you want to fly to San Francisco, searching by month will show you the cheapest times to go. It’s also worth looking out for flights operated by Virgin Atlantic, British Airways & KLM, as they're the most popular airlines for this journey.

Flights from Southampton to San Francisco normally take 16 hrs 5 mins. Make sure you check what refreshments or meals are included, so you can plan your journey. Before you book, why not check out our holiday package and car hire options? We have some hotels close to the airport – handy if you're arriving late at night, or flying back very early.

Other popular destinations near San Francisco

Where other people are flying to

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