You’ve searched for flights from Southampton to Panama City. We've gone through all five flights that go to or via Panama City every week, to help you find the cheapest flight. KLM usually has the best-value flights from Southampton, but make sure you compare all your options to get the cheapest flight possible.
We scan thousands of airfares from hundreds of airlines across the globe. We've found that one airlines operate the 8415 km flight from Southampton to Panama City. Flights during peak season tend to be the most expensive – so if you want to go during that time, it's best to book early. Or you could try to get a last-minute flight deal.
To sort cheap flights to Panama City, it's best to start searching for flights by month, as this will show you when prices are at their lowest. Keep an eye on KLM too, as they're the most popular airline for flying from Southampton to Panama City.
It takes about 12 hrs 30 mins to fly from Southampton to Panama City. Once you’ve chosen your flight, go through and fill out your details to complete your booking. If you haven’t yet sorted your hotel or car hire, take a look at our competitive rates – then you can book your flights and accommodation in one go.