We've compared all ten flights that go to or via Des Moines every week, to find the best deal for you. Virgin Atlantic usually has the cheapest flights from Southampton to Des Moines, so keep an eye out for them in your search results. If they’re not the cheapest option, try searching by month to compare costs throughout the week.
When you fly from Southampton to Des Moines, you'll have one airlines to choose from for your 6707 km journey. If you're planning to fly in peak season, make sure you book in advance to get a reasonable price. Or you could hold on and try to get a last-minute bargain.
If you're fairly flexible about when you want to fly to Des Moines, searching by month will show you the cheapest times to go. It’s also worth looking out for flights operated by Virgin Atlantic, as they're the most popular airlines for this journey.
Flights from Southampton to Des Moines normally take 17 hrs 40 mins. Make sure you check what refreshments or meals are included, so you can plan your journey. Before you book, why not check out our holiday package and car hire options? We have some hotels close to the airport – handy if you're arriving late at night, or flying back very early.
