Your flight from Manchester to Chicago should take about 12 hrs 45 mins. We've gone through all 499 of the weekly flights to or via Chicago, operated by nine airlines, to help you compare flight prices and times. At the moment, the cheapest flight is £462.
Being flexible with your dates could help you find a cheaper flight from Manchester to Chicago.
In Chicago, Chicago O'hare International Airport (ORD) is usually the cheapest airport to fly to, but there are two airports to choose from. Not sure who to fly with? Finnair, Virgin Atlantic & Lufthansa are the most popular airlines available from Manchester.
If you can’t quite find what you’re looking for, try checking flight prices to other cities in the USA. Netflights has scanned 7,105 flights across the globe – and that's just today – so you're bound to find one that works for you.